The Importance of HPV Testing and Cervical Cancer Prevention

Testing for Human Papilloma Virus (HPV) has been used more frequently over the past decade in helping clinicians decide how to manage abnormal Pap test results. In accordance with national guidelines, Women’s Health Associates is using HPV testing along with Pap test (together called co-testing) to improve the sensitivity of screening Pap tests.    

Specific strains of HPV are necessary for the development of cervical cancer. Unlike other forms of cancer that can be attributed to hereditary influences, cervical cancer is largely caused by environmental factors (the presence of HPV). In fact, women without the specific high-risk strains of HPV have virtually no risk of developing cervical cancer.

Pap tests alone identify potentially abnormal cells on the cervix, but further testing, often including biopsies, is then necessary to: 1) confirm the actual presence of abnormal cells and 2) determine if the abnormality is a benign change that can be followed conservatively or if the abnormality is a precancerous change that requires closer follow-up or treatment. With co-testing, there’s potential to find more high-risk abnormalities sooner (if HPV is positive) and the opportunity to avoid unnecessary biopsies (if HPV is negative).

Only certain strains of HPV cause cancer. Other strains (low-risk strains that are not tested for) may cause genital warts or benign changes (not precancerous) in the cervical cells, which will also cause an abnormal Pap test. It is exceedingly rare for HPV to cause problems in pregnancy for baby or mother. Another notable point about HPV is that it takes five to seven years for cervical cancer to develop after the initial infection.

 

Age 20

High-risk HPV is extremely common in younger women (under 29), but it is less likely to persist. As younger women often clear HPV in a year or two, they are much less likely to develop cancer. That’s why the age to begin Pap screening was increased to 21, and routine HPV testing in this age group is not as helpful.

Because of a higher prevalence of chlamydia in women under 25, routine screening for sexually transmitted diseases is also recommended for this age group. These types of infections can cause scarring and damage to the fallopian tubes, which significantly decreases the chance of fertilization.

It is now recommended to begin Pap test screening at age 21 and to repeat Pap testing in three years, if normal. If the Pap test is abnormal, yearly Pap testing, HPV testing or other testing may be indicated.

Age 30

At age 30, Women’s Health Associates is offering co-testing (Pap and HPV). If both are negative, and if the last three consecutive Pap tests were normal, co-testing can be repeated in five years. Of course, with problems, concerns or other issues, the Pap can be repeated sooner at the provider’s discretion.

Over 30

In patients without a history of high-risk disease (precancerous lesions), it may be reasonable to stop Pap screening after hysterectomy (if the cervix is completely removed) or after the age of 65.